DiaSys GLDH FS DGKC is an optimized UV test to determine glutamate dehydrogenase activity in serum or plasma on photometric systems. For veterinary or research use only. Glutamate dehydrogenase (GLDH) is a mitochondrial enzyme, which is localized in all tissues but predominantly expressed in theliver. Significant elevations of the GLDH activity are detected in necrosis of hepatocytes, in acute toxic liver necrosis and in hypoxic liver diseases. Moreover, measurement ofGLDH activity is a pivotal tool for the evaluation of the damage severity of parenchymal cells. The test has a wide measuring range from 3 U/L to 130 U/L and interfernces are minimized. Method: Optimized UV test, according to recommendations of the DGKC(German Society of Clinical Chemistry) Reagent 1 contains Triethanolamine, α-Ketoglutarate, Ammino Acetate, EDTA, ADP, and LDH, reagent 2 contains NADH. Reagents must be stored refrigerated.